Investigational Drug Branch (IDB)
About IDB
Dr. Steven Gore is CTEP's Investigational Drug Branch Chief.
The Investigational Drug Branch manages NCI's innovative early phase experimental therapeutics program, which has contributed to the clinical development of anticancer agents since the early 1970s. Through this program, hundreds of agents, both small molecule and immunologic, have been made available for collaborative development.
IDB has scientific oversight of the NCI's Experimental Therapeutics Clinical Trials Network (ETCTN), which performs clinical studies of promising anti-cancer agents in collaboration with the academic and pharmaceutical industry research communities.
Read more about CTEP's end-to-end support for novel anti-cancer agent development.
IDB physicians work with ETCTN investigators and industry partners to drive the clinical development of NCI-IND agents, including:
- Reviewing and prioritizing clinical trial proposals
- Monitoring ETCTN clinical trials for safety and efficacy
- Investigating and preparing reports concerning adverse events (AEs) for the NCI-IND agents
- Working closely with the Investigational Drug Steering Committee to increase the transparency and openness of the trial design and prioritization process.
ETCTN investigators can learn more about designing and submitting a Letter of Intent (LOI) on our Trial Development Resources page or find the IDB drug monitor for a particular agent by reviewing the list of Agents Available Under CTEP CRADAs.
CTEP IDB Staff Directory
| Name | Role | Email Address |
|---|---|---|
| Steven Gore, M.D. | Branch Chief | steven.gore@nih.gov |
| Helen X. Chen, M.D. | Associate Branch Chief (Immunooncology) | helen.chen@nih.gov |
| Andrecia Cunningham, M.S., B.S.N. | Clinical Operations Manager | andrecia.cunningham@nih.gov |
| Brian Ko, M.D. | Medical Officer (Immunooncology) | brian.ko@nih.gov |
| Lorraine Pelosof, M.D., Ph.D. | Medical Officer (Small molecules, epigenetics) | lorraine.pelosof@nih.gov |
| Cheryl Pickett-Gies, M.D., Ph.D. | Medical Officer (Immunooncology) | cheryl.pickett@nih.gov |
| Nicole Pultar | Administrative Assistant | nicole.pultar@nih.gov |