Cancer Therapy Evaluation Program (CTEP)

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The Cancer Therapy Evaluation Program (CTEP) manages a broad range of clinical trials that are closely integrated with preclinical discovery and development and biostatistical expertise fostered by other DCTD programs.
Once a treatment approach has demonstrated promising efficacy and adequate safety in preclinical testing, CTEP-supported clinical trials networks and resources can move the therapy from first-in-human safety trials through definitive, randomized, controlled trials.
CTEP also provides centralized infrastructure and support for other NCI-supported clinical trials networks, improving efficiency and reducing costs.
About CTEP
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CTEP Organization
CTEP consists of the Office of the Associate Director (OAD) and seven branches that provide unique expertise.
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About CTEP's Support for Trials
Discover how a CTEP-supported network trial goes from an idea to practice-changing results.
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Clinical Grants and Contracts Portfolio
CTEP's Clinical Grants and Contracts Branch supports a broad portfolio of research projects, including multidisciplinary, long-term research program projects, discrete investigator-initiated projects, and complex cooperative agreements.
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CTEP Resources for Network Trials
CTEP's Clinical Trials Monitoring Branch (CTMB), Clinical Trials Operations and Informatics Branch (CTOIB), Pharmaceutical Management Branch (PMB), and Regulatory Affairs Branch (RAB) provide critical services for trial activation and operations.
CTEP-Supported Clinical Trial Networks
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NCI's National Clinical Trials Network: NCTN
The NCTN conducts large-scale, national, oncology treatment and advanced imaging clinical trials using an integrated and collaborative network infrastructure.
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Experimental Therapeutics Clinical Trials Network: ETCTN
The ETCTN conducts early clinical trials of innovative cancer therapies using a coordinated team-based approach.
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Pediatric Clinical Trials Networks
The Pediatric Early Phase Clinical Trials Network (PEP-CTN) and Pediatric Brain Tumor Consortium (PBTC) conduct trials to identify effective new agents for children and adolescents with cancer.
Active and Upcoming Clinical Trials
View PDFs showing the latest portfolio of CTEP-supported cancer clinical trials open to enrollment in the NCTN and open or upcoming in the ETCTN (updated monthly).
NCTN Trials by Cancer Type
- All NCTN Trials
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Adult Trials
- Brain Cancer Trials
- Breast Cancer Trials
- Endocrine Cancer Trials
- Gastrointestinal (GI) Cancer Trials
- Genitourinary (GU) Cancer Trials
- Gynecologic Cancer Trials
- Head and Neck Cancer Trials
- Leukemia Trials
- Lymphoma Trials
- Melanoma and Other Skin Cancer Trials
- Myeloma Trials
- Sarcoma Trials
- Thoracic Cancer Trials
Pediatric and AYA Trials
- Pediatric Brain Cancer Trials
- Pediatric Hematological Trials
- Pediatric Solid Tumor Trials
- Adolescent and Young Adult (AYA) Trials
ETCTN Trials
- All ETCTN Trials
- Radiation Trials
Trials by Cancer Type
- Brain Cancer Trials
- Breast Cancer Trials
- Endocrine/Neuroendocrine Cancer Trials
- Gastrointestinal (GI) Cancer Trials
- Genitourinary (GU) Cancer Trials
- Gynecologic Cancer Trials
- Head and Neck/Thyroid Cancer Trials
- Leukemia Trials
- Lung Cancer Trials
- Lymphoma Trials
- Melanoma and Other Skin Cancer Trials
- Myeloma Trials
- Sarcoma Trials
Trials in Solid Tumors
- Solid Tumors with specific mutations
- Solid tumors, no specified mutations
- Dose-escalation in Solid Tumors (disease-specific expansion)