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Optimal Two-Stage Phase II Design Software

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This file provides an easy to use, fast compiled C program that runs in a DOS window for computing optimal and minimax two-stage designs for phase II clinical trials. The program is based on the paper by R. Simon: "Optimal two stage designs for phase II clinical trials", Controlled Clinical Trials 10:1-10, 1989. To use the program, open a DOS window using the command prompt menu item in your start menu. CD to the directory into which you have put the file, and execute it.

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