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pCR Trial-Level Surrogate Analysis Software

This is an R source package that contains the code, data, documentation, and results of the analysis reported in "Assessing pathological complete response as a trial-level surrogate endpoint for early-stage breast cancer" and supplement, by E. L. Korn, M. C. Sachs, & L. M. McShane, Ann Oncol 27: 10-15, 2016.

The package is organized as follows:

  • DESCRIPTION details the analysis and documents the dependencies.
  • The /data subdirectory contains the data files in .csv and .RData formats. The data sets are documented in the /man directory.
  • The /inst/doc directory contains the code and results of the analysis.
  • The /R directory has the R functions that were used in the analysis.
  • The /man directory contains the documentation in Rd format. View the documentation in R by typing ?pcrmeta.

Download and Install

  1. Download the source file:
    Download pcrmeta_0.4.1.tar.gz

  2. Type this command:

    install.packages("pcrmeta_0.4.1.tar.gz", type = "source", repos = NULL)
  3. Load the package by typing library(pcrmeta)
  4. View the help files by typing ?pcrmeta

If you would like to reproduce some or all of this content, see Reuse of NCI Information for guidance about copyright and permissions. In the case of permitted digital reproduction, please credit the National Cancer Institute as the source and link to the original NCI product using the original product's title; e.g., “pCR Trial-Level Surrogate Analysis Software was originally published by the National Cancer Institute.”

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