Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

R Shiny applications

R Shiny Applications for Online Sample Size Calculation

Developed by Dr. Richard Simon and the Biometric Research Program, National Cancer Institute

These applications work best with latest versions of Firefox or Chrome. They have not been tested with other browsers. The web applications are developed using the Shiny package from RStudio.

For questions and comments on these applications, please contact the Biometric Research Program.

Design, Monitoring and Analysis of Bayesian Basket Discovery Trials
Bayesian Phase II Single Arm Clinical Trials - Binary Outcomes
Bayesian Phase II Single Arm Clinical Trials - Time to Event Outcomes