Li Jia, Ph.D.
Dr. Jia serves as the Biomedical Informatics Project Manager in the Clinical Trials Operations and Informatics Branch (CTOIB), where she focuses on information technology, emerging technologies, and other initiatives.
She leads cybersecurity efforts across CTEP IT teams, monitoring and addressing system vulnerabilities and refining security incident response processes. As the coordinator for CTEP's cloud migration efforts, she oversees the phased transition of CTEP systems to the NCI cloud. Additionally, she provides oversight for contracts of Identity Proofing and Verification processes and the CTEP Enterprise System.
With a strong background in bioinformatics and computational biology for cancer research, Dr. Jia has expertise in data analysis, data management, and data science. Her professional interests include applying machine learning (ML) and Artificial Intelligence (AI) models within CTEP systems, as well as advancing data analysis and management for clinical trial data. She is also actively engaged in efforts to streamline clinical trials and enhance integration with electronic health records (EHR).
Selected Publications
Lowery FJ, Krishna S, Yossef R, Parikh NB, Chatani PD, Zacharakis N, Parkhurst MR, Levin N, Sachs A, Sindri S, Lu Y, Jia L, Gartner JJ, Hill V, Copeland AR, Kivitz S, Nah SK, Paria BC, Florentin M1, Ngo LT, Ray S, Shindorf M, Shepherd R, Toy C, Parikh A, Prickett TJ, Kelly MC, Beyer R, Goff SL, Yang JC, Robbins PF, Rosenberg SA. Molecular signature of antitumor neoantigen-reactive T cells from metastatic human cancers. Science. Feb 3, 2022; 375(6583):877-884. Doi: 10.1126/science.abl5447.
Krishna S, Lowery FJ, Copeland A, Bahadiroglu E, Mukherjee R, Jia L, Anibal JT, Sachs A, Adebola SO, Gurusamy D, Yu ZY, Hill V, Gartner JJ, Li Y, Parkhurst M, Paria B, Kvitsborg P, Kelly M, Goff SL, Altan-Bonnet G, Robbins PF, Rosenberg SA. Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer. Science. Dec 11, 2020; Vol. 370, Issue 6522, pp. 1328-1334
Lu Y, Jia L, Zheng Z, Tran E, Robbins PF, Rosenberg SA. Single-Cell transcriptome analysis reveals gene signatures associated with T-cell persistence following adoptive cell therapy. Cancer Immunol. Res. November 2019. DOI: 10.1158/2326-6066.CIR-19-0299
Doran SL, Stevanovic S, Adhikary S, Gartner JJ, Jia L, Kwong M, Faquin WC, Hewitt, SM, Sherry RM, Yang JC, Rosenberg SA, Hinrichs CS. T-Cell receptor gene therapy for human papillomavirus-associated epithelial cancers: A First-in-Human, phase I/II study. J Clin Oncol. Oct 20, 2019; 20;37(30):2759-2768. DOI: 10.1200/JCO.18.02424
Gara S, Jia L, Marino M, Agarwal S, Zhang L, Cam M, Patel D, Kebebew E. HAPB2 in Familial Papillary Thyroid Cancer. New England Journal of Medicine. 2015; 373:2084-2087. DOI: 10.1056/NEJMc1511631. Nov 19, 2015