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Dog Oncology Grant Supplement (DOGS) Program

A light tan dog lays in the grass

The DOGS Program supports collaborative, multidisciplinary research in canine oncology that intersects with two or more of the following areas: immuno-oncology (IO), radiation treatment (RT), and imaging. Data generated by the administrative supplement awards will be deposited into the Integrated Canine Data Commons.

Goals

  • Leverage the existing NCI infrastructure in companion canine cancer research to facilitate new high-quality collaborative opportunities that integrate across approaches in IO, imaging, and RT
  • Enable new cross-correlatives and response measures to optimize treatment approaches using companion canine cancer research to maximize the translational benefits for people with cancer

Award Structure

Awards are being shared between a current NCI grantee and at least one partnering collaborator who is not named on the parent award. Either the PI of the parent award or the collaborator must have canine cancer research expertise. DOGS-eligible parent awards must have an NCI primary assignment through any of the following mechanisms: R01, R37, U01, P01, P30, P50, U19, U24, or U54.

Awardees

SubjectParent GrantSupplement PI(s)CoinvestigatorsCollaborating Teams
Using myeloid-targeted immunotherapy and radiation therapy to treat sinonasal carcinoma in dogsP50CA261605; Colorado Head and Neck Cancer SPORE (Jimeno, Antonio); University of Colorado DenverMary-Keara BossSteven Dow, Lyndah Chow, Daniel ReganUniversity of Colorado Denver, Colorado State University, UC Davis
Validating PET imaging as a non-invasive platform to study CAR T cell dynamics in canine lymphomaR37CA266344; Towards safer and more effective CAR T Cell therapy through the modulation of myeloid cytokines (Kenderian, Saad); Mayo Clinic RochesterSaad Kenderian and Wesley WiersonJeffrey Bryan, Alex AbelMayo Clinic Rochester, LifEngine Animal Health (LEAH) Labs, University of Missouri Veterinary Health Center

Contact

Connie Sommers, Ph.D. (sommersc@mail.nih.gov)

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