Dog Oncology Grant Supplement (DOGS) Program

The DOGS Program supports collaborative, multidisciplinary research in canine oncology that intersects with two or more of the following areas: immuno-oncology (IO), radiation treatment (RT), and imaging. Data generated by the administrative supplement awards will be deposited into the Integrated Canine Data Commons.

Goals

Leverage the existing NCI infrastructure in companion canine cancer research to facilitate new high-quality collaborative opportunities that integrate across approaches in IO, imaging, and RT
Enable new cross-correlatives and response measures to optimize treatment approaches using companion canine cancer research to maximize the translational benefits for people with cancer

Award Structure

Awards are being shared between a current NCI grantee and at least one partnering collaborator who is not named on the parent award. Either the PI of the parent award or the collaborator must have canine cancer research expertise. DOGS-eligible parent awards must have an NCI primary assignment through any of the following mechanisms: R01, R37, U01, P01, P30, P50, U19, U24, or U54.

Awardees

Subject	Parent Grant	Supplement PI(s)	Coinvestigators	Collaborating Teams
Using myeloid-targeted immunotherapy and radiation therapy to treat sinonasal carcinoma in dogs	P50CA261605; Colorado Head and Neck Cancer SPORE (Jimeno, Antonio); University of Colorado Denver	Mary-Keara Boss	Steven Dow, Lyndah Chow, Daniel Regan	University of Colorado Denver, Colorado State University, UC Davis
Validating PET imaging as a non-invasive platform to study CAR T cell dynamics in canine lymphoma	R37CA266344; Towards safer and more effective CAR T Cell therapy through the modulation of myeloid cytokines (Kenderian, Saad); Mayo Clinic Rochester	Saad Kenderian and Wesley Wierson	Jeffrey Bryan, Alex Abel	Mayo Clinic Rochester, LifEngine Animal Health (LEAH) Labs, University of Missouri Veterinary Health Center

Contact

Connie Sommers, Ph.D. (sommersc@mail.nih.gov)