Skip to main content
An official website of the United States government
Email

GMD tables (supplementary material, Clin. Epigenet. paper)

Supplementary resource for

“Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines”

  • Authors: Suleyman Vural, Alida Palmisano, William C. Reinhold, Yves Pommier, Beverly A. Teicher, Julia Krushkal
  • Clinical Epigenet 13, 49 (2021)
  • View Abstract
  • View Publication

Altered DNA methylation patterns play important roles in cancer development and progression. We examined whether expression levels of genes directly or indirectly involved in DNA methylation and demethylation may be associated with response of cancer cell lines to chemotherapy treatment comprising a variety of antitumor agents.

We analyzed 72 genes encoding epigenetic factors directly or indirectly involved in DNA methylation and demethylation processes. We analyzed data from 645 cancer cell lines and 23 cancer types from the Cancer Cell Line Encyclopedia and Genomics of Drug Sensitivity in Cancer datasets. We observed numerous correlations between expression of genes encoding epigenetic factors and response to chemotherapeutic agents.

Access the searchable, dynamic GMD tables resource

Each link at the GMD tables web portal opens in a separate tab, and displays dynamic tables using the DataTables JavaScript library. Google Chrome and Firefox are the preferred browsers to view and interact with the tables.

*Disclaimer*: the information provided is a free resource intended for research purposes only. It should NOT be used for emergencies or medical or professional advice.

Email