2019 Alliance for Nanotechnology in Cancer Principal Investigators’ Meeting

8:30 – 9:00 a.m.

Welcome and Introduction

• Doug Lowy, M.D., Acting Director, National Cancer Institute

• Janet Eary, M.D., Associate Director, Cancer Imaging Program, DCTD, National Cancer Institute

• Piotr Grodzinski, Ph.D., Branch Chief, NSDB/CIP/DCTD, National Cancer Institute

Session I

Moderator: Piotr Grodzinski, Ph.D., National Cancer Institute

9:00 – 9:35 a.m.

UCLA/Caltech/ISB Center Highlights and Takeaways

James Heath, Ph.D., Institute for Systems Biology

9:35 – 10:10 a.m.

MSKCC-Cornell Center Highlights and Takeaways

Michelle Bradbury, Ph.D, M.D., Memorial Sloan Kettering Cancer Center

10:10 – 10:30 a.m.

Break

10:30 – 11:15 a.m.

Keynote Presentation: Nanomedicine: Past, Present, and Future

Omid Farokhzad, M.D., M.B.A., Brigham and Women’s Hospital

11:15 a.m. – 12:00 p.m.

Keynote Presentation: Most Pressing Needs in Cancer Research and Oncology in Context of New Technology Development

Phuoc Tran, M.D., Ph.D., Johns Hopkins University

12:00 – 1:15 p.m.

Lunch

Session II

Moderator: Christopher Hartshorn, Ph.D., National Cancer Institute

1:15 – 1:35 p.m.

Effective Delivery of a Therapeutic Monoclonal Antibody to Metastases in the Central Nervous System of Mice Via Polymer Encapsulation and Receptor Targeting

Masakazu Kamata, Ph.D., UCLA

1:35 – 1:55 p.m.

Novel Approach to Attenuate Small Lung Cancer Growth and Metastasis

Wasim Nasser, Ph.D., University of Nebraska Medical Center

1:55 – 2:15 p.m.

Wireless Nano-Optogenetic Immunotherapy

Gang Han, Ph.D., University of Massachusetts Worchester

2:15 – 2:45 p.m.

Imaging the Delivery and Action of Nanomaterials in Vivo: An Update of MGH IRCN Progress

Miles Miller, Ph.D., Massachusetts General Hospital

2:45 – 3:15 p.m.

Break and Alliance Celebration

3:15 – 4:`35 p.m.

T32 Program Overviews

• Jianghong Rao, Ph.D., Stanford University CNTC

• Konstantin Sokolov, Ph.D., The University of Texas MD Anderson CNTC

• Alexander Stegh, Ph.D., Northwestern University CNTC

• Andrew Kummel, Ph.D., University of California, San Diego CNTC

• Alexander Kabanov, Ph.D., The University of North Carolina at Chapel Hill CNTC

5:15 – 6:15 p.m.

Coordination and Governance Committee Meeting

By invitation only. Rm. 2W910

Session III

Moderator: Christopher Hartshorn, Ph.D., National Cancer Institute

9:00 – 9:35 a.m.

UNC Chapel Hill Center Highlights and Takeaways

Leaf Huang, Ph.D., University of North Carolina at Chapel Hill

9:35 – 10:10 a.m.

WUSTL Center Highlights and Takeaways

Sam Achilefu, Ph.D., Washington University in St. Louis

10:10 – 10:30 a.m.

Break

10:30 – 11:05 a.m.

Northwestern Center Highlights and Takeaways 

Chad Mirkin, Ph.D., Northwestern University

11:05 – 11:35 a.m.

Use of a Silicasome Nanoparticle platform for Treatment of Pancreatic Ductal Adenocarcinoma

Huan Meng, Ph.D., UCLA

11:35 – 11:55 a.m.

Whitlockite Nanoparticle-based Immunotherapy for Bone Metastasis

Shiladitya Sengupta, Ph.D., Brigham and Women’s Hospital

11:55 a.m. – 1:10 p.m.

Lunch

Session IV

Moderator: Luisa Russell, Ph.D., National Cancer Institute

1:10 – 1:30 p.m.

UNC Clinical/Scientific Highlight Talk

Andrew Wang, M.D., University of North Carolina at Chapel Hill

1:30 – 1:50 p.m.

Northwestern Clinical/Scientific Highlight Talk – Spherical Nucleic Acid Nanotechnology for Cancer Immunotherapy: Advance to Clinical Evaluation and Rational Development of Vaccines

Andrew Lee, Ph.D., Northwestern University

1:50 – 2:10 p.m.

WUSTL Clinical/Scientific Highlight Talk

Gregory Lanza, M.D., Ph.D., Washington University in St. Louis

2:10 – 2:30 p.m.

Stanford Clinical/Scientific Highlight Talk

Alice Fan, M.D., Stanford University

2:30 – 2:50 p.m.

MSKCC-Cornell Clinical/Scientific Highlight Talk

Michelle Bradbury, Ph.D., M.D., Memorial Sloan Kettering Cancer Center

2:50 – 3:10 p.m.

UCLA/Caltech/ISB Clinical/Scientific Highlight Talk

Wei Wei, Ph.D., Institute for Systems Biology

3:10 – 3:30 p.m.

Break

3:30 – 3:50 p.m.

Nanoparticles for the Treatment of Intraperitoneal Mesothelioma: Enhancing Tumor Localization and Increasing Drug-Loading for Improved Efficacy

Mark Grinstaff, Ph.D., Boston University

3:50 – 4:20 p.m.

The Rodent Eye as a Non-invasive Window for Understanding Cancer Nanotherapeutics

Kit Lam, Ph.D., UC Davis

4:20 – 4:40 p.m.

Folate-Displaying Exosome Mediated Cytosolic Delivery of siRNA Avoiding Endosome Trapping

Peixuan Guo, Ph.D., Ohio State

4:40 – 5:00 p.m.

Alliance Achievements by the Numbers

Piotr Grodzinski, Ph.D., National Cancer Institute

5:00 – 6:00 p.m.

Poster Session, 2nd Floor Atrium

Session V

Moderator: Christina Liu, Ph.D. P.E., National Cancer Institute

9:00 – 9:35 a.m.

Stanford Center Highlights and Takeaways

Shan Wang, Ph.D., Stanford University

9:35 – 10:05 a.m.

Nanostructure-Embedded Microchips for Liquid Biopsy in Cancer

• Hsian Rong Tseng, Ph.D., UCLA

• Edwin Posadas, M.D., Cedars-Sinai Medical Center

10:05 – 10:25 a.m.

Break

10:25 – 10:55 a.m.

Targeted Core Shell Nanogels for Triple Negative Breast Cancer

Alexander Kabanov, Ph.D., University of North Carolina at Chapel Hill

10:55 – 11:25 a.m.

Co-delivery of Targeted Stroma-breaking Theranostic Nanoparticle and Immune Checkpoint Nano-PD-L1 Inhibitor for the Treatment of Pancreatic Cancer

Lily Yang, M.D., Ph.D., Emory University

11:25 – 11:55 a.m.

Nanoscale Metal-organic Frameworks for Light Triggered and X-ray Induced Photodynamic Therapy of Head and Neck Cancers

Wenbin Lin, Ph.D., University of Chicago

11:55 p.m. – 12:25 p.m.

Delivery of Drugs to Brain Tumors Using Multicomponent Nanoparticles

Efstathios Karathanasis, Ph.D., Case Western Reserve University

12:25 – 12:55 p.m.

Poster Prizes and Closing Comments

Piotr Grodzinski, Ph.D., National Cancer Institute

1:00 p.m.

Adjournment