The Information Technology Branch (ITB)

Support for DTP and DCTD

The Information Technology Branch (ITB) manages chemical and biological databases to support ongoing research efforts of the DTP. ITB employs modern software and hardware facilities to provide support for DTP and engages in collaborative research to promote further implementation of information technology. ITB provides computational chemistry and molecular modeling support for DTP and DCTD projects. ITB is also primarily responsible for preparing DTP data for release to the research community.

Current Projects at DTP

DCTD Pharmacological Datawarehouse

The DCTD Pharmacological Dashboard and Datawarehouse provides a central location for harmonization of data from various research efforts at DTP and DCTD. In this manner, we hope to provide users a one-stop shop for data on compounds that have been tested at DTP.

HTS-384 NCI-60 Human Tumor Cell Lines Screen

ITB has partnered with the Molecular Pharmacology Branch (MPB) to develop the web application and database that assist the lab with their experiments. This is now in production.

Studies in Applications of AI at DTP

The members of ITB are also endeavoring to help facilitate and implement solutions that leverage AI such as Large Language Models (LLM). This is an ongoing effort as the technology in this area is expanding rapidly in breadth and depth