Dr. Jeffrey C. Buchsbaum, M.D., Ph.D., A.M.

Dr. Buchsbaum's programmatic experience includes membership on teams conducting the development, evaluation, and management of multi-disciplinary research programs and consortia. He contributes to CTEP review, grants management, and unique opportunities for science associated with new technologies such as hadron therapy, biosensors, and the interface of missions across the USG - looking at quality assurance, pediatric radiation therapy, LINAC research, biologic dose optimization, digital twins, predictive oncology, quantum science, international collaborations, and late effects. He is the senior pediatric radiation oncologist on the main NIH campus.

Dr. Buchsbaum completed a master's degree in computational physics in his senior year of college at Dartmouth. He then went to Johns Hopkins and completed an MD/PhD combined degree in molecular biophysics and biophysical chemistry under Jeremy Berg. He then completed formal clinical training at the Cleveland Clinic in radiation oncology, in which he is board certified, and developed a funded research program as a resident. He then went to St. Jude as faculty under Larry Kun and others developing translational skills including being on structural biology teams and CNS protocol teams. From Memphis his career included positions in Pennsylvania, Florida and most recently Indiana. His final academic position before joining NCI in 2016 was that of Professor in the Departments of Radiation Oncology, Pediatrics, Neurosurgery and Physics at Indiana University where he was a leader at the proton therapy center in Bloomington. He has founded and been on the boards of several non-profits, and has additional certifications in GKRS, CKRS, and brachytherapy.

 Selected Publications

•    Coleman CN*, Buchsbaum JC*, Prasanna PGS, Capala J, Obcemea C, Espey MG, Ahmed MM, Hong JA, Vikram B. Moving Forward in the Next Decade: Radiation Oncology Sciences for Patient-Centered Cancer Care. JNCI Cancer Spectr. 2021 May 17;5(4). *Contributed equally.

•    Buchsbaum J, Capala J, Obcemea C, Keppel C, Asai M, Chen GH, Christy ME, Fakhri GE, Gueye P, Pogue B, Ruckman L, Tourassi G, Vetter K, Zhao W, Squires A, Saboury B, Wang G, Domurat-Sousa K, Weisenberger A. The United States Department of Energy and National Institutes of Health Collaboration: Medical Care Advances by Discovery in Radiation Detection. Med Phys. 2024 Dec;51(12):8654-8669.

•    Paganetti H, Simone CB 2nd, Bosch WR, Haas-Kogan D, Kirsch DG, Li H, Liang X, Liu W, Mahajan A, Story MD, Taylor PA, Willers H, Xiao Y, Buchsbaum JC. NRG Oncology White Paper on the Relative Biolgical Effectiveness in Proton Therapy. Int J Radiat Biol Phys. 2025 Jan 1;121(1):202-217.

•    Buchsbaum JC, Jaffray DA, Ba D, Borkon LL, Chalk C, Chung C, Coleman MA, Coleman CN, Diehn M, Droegemeier KK, Enderling H, Espey MG, Greenspan EJ, Hartshorn CM, Hoang T, Hsiao HT, Keppel C, Moore NW, Prior F, Stahlberg EA, Tourassi G, Willcox KE. Predictive Radiation Oncology - A New NCI-DOE Scientific Space and Community. Radiat Res. 2022 Apr 1;197(4):434-445.

•    Buchsbaum JC, Espey MG, Obcemea C, Capala J, Ahmed M, Prasanna PG, Vikram B, Hong JA, Teicher B, Aryankalayil MJ, Bylicky MA, Coleman CN. Tumor Heterogeneity Research and Innovation in Biologically Based Radiation Therapy From the National Cancer Institute Radiation Research Program Portfolio. J Clin Oncol. 2022 Jun 10;40(17):1861-1869

Additional Links to Scientific Publications

•    Google Scholar

Education

•    Ph.D., Molecular Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD

•    M.D., Johns Hopkins University School of Medicine, Baltimore, MD

•    A.M. (M.S. equivalent), Physics, Dartmouth College, Hanover, NH

•    A.B. (B.S. equivalent), Physics and Psychology, Dartmouth College, Hanover, NH