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Dr. Huiming Zhang serves as the Program Director in the Image Technology Development Branch of the Cancer Imaging Program within the Division of Cancer Treatment and Diagnosis at the National Cancer Institute (NCI). She earned her Ph.D. in solid-state NMR Biophysics from the University of Louisville and completed postdoctoral training at the University of Virginia. 

Dr. Zhang has a diverse background in NMR, MRI, and Molecular imaging. She has held several positions, including instructor in the Biochemistry Department at the University of Chicago, senior NMR spectroscopist at the Evanston Northwestern Healthcare Research Institute, and research assistant professor at the Radiology Department of Northwestern University. Additionally, she served as a scientific imaging editor for the NIH Molecular Imaging Contrast Agent Database (MICAD). 

Her research interests include enzyme dynamics through solid-state NMR, protein structures using high-resolution NMR, pharmacological effects by preclinical functional MRI. She also focused on MRI contrast agents and mechanisms, NMR/MRI instrumentation and hardware, image data processing, and molecular/metabolic imaging. In 2009, Dr. Zhang joined the NCI Cancer Imaging Program as a program director. She has organized international workshops on hyperpolarized 13C MRI, diffusion-weighted MRI, metabolic imaging, and quantitative MRI, and led a meeting session on quantitative PET/CT. She leads and manages the NCI Co-Clinical Imaging Research Resources (CIRP) program.

Selected Publications

  1. Zhang H, Kulshrestha NP, Woehler SE, Wittebort RJ.  Alkyl dynamic in perovskite bilayers and their variation with structural phase as studied by powder and single crystal NMR, J. Chem Phys.  105: 2891, 1996. https://doi.org/10.1063/1.472151
  2. Zhang H, Bryant RG.  Bound ligand motion in crystalline carboxypeptidase A, Biophys. J, 72: 363, 1997. https://pmc.ncbi.nlm.nih.gov/articles/PMC1184325
  3. Zhang H, Xie, Y, Ji T, Diffusion-exchange effect on the paramagnetic relaxation enhancement in off-resonance rotating frame. J. Magn. Reson, 186:259-272 (2007). https://pmc.ncbi.nlm.nih.gov/articles/PMC2041893
  4. Zhang H. The potential of hyperpolarized (13)C MRI in assessing signaling pathways in cancer. Acad Radiol, 21:215, 2014. https://pubmed.ncbi.nlm.nih.gov/24439335
  5. Zhang H. The National Cancer Institute’s co-clinical quantitative Imaging research resources for precision medicine in preclinical and clinical setting, Tomography, 9, 931-941, 2023. https://pmc.ncbi.nlm.nih.gov/articles/PMC10204454

Education

  • Ph.D., Biophysics, University of Louisville
  • M.S., Physical Chemistry, Academia Sinica, Institute of Chemistry
  • B.S., Coordination Chemistry, Wuhan University
  • Updated:
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