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DCTD’s Translational Research Program Announces Fiscal Year 2025 SPORE Grantees

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The Translational Research Program (TRP) recently announced its successfully competed FY2025 Specialized Programs of Research Excellence (SPORE) grantees.

The SPORE program uses the P50 and U54 grant funding mechanisms to promote collaborative, interdisciplinary, translational cancer multi-project research. SPOREs are primarily focused on organ site disease, but also on themes that cut across organ sites.

There are now 56 funded SPOREs, including traditional P50 SPORE grants as well as the U54 RFA SPORE awards in Cancer Health Disparities, located at academic centers in 32 states.

FY 2025 SPORE Grantees

Principal InvestigatorInstitutionCancer Type
Isabella Rosa-Cunha; Erin Kobetz; Lisa Flowers and James LillardUniversity of Miami, Emory University, and Morehouse School of MedicineAnal and Cervical
*Kornelia Polyak; Leif Ellisen; Nancy Lin; Geoffrey ShapiroDana-Farber Cancer Institute and Harvard Cancer CenterBreast
Victoria Bae-Jump and Hazel NicholsUniversity of North Carolina, Chapel HillEndometrial
*Robert CoffeyVanderbilt University Medical CenterGastrointestinal
Monica Gramatges; Philip Lupo and Karen RabinBaylor College of Medicine, Emory University and University of California, San FranciscoLeukemia
Amit Singal and Yujin HoshidaUniversity of Texas Southwestern Medical CenterLiver
*Roy Herbst and Katerina PolitiYale UniversityLung
*A. McGarry HoughtonFred Hutchinson Cancer Research CenterLung
Christopher Flowers and Jean KoffUniversity of Texas MD Anderson Cancer Center and Winship Cancer Institute of Emory UniversityLymphoma
Susan Chang and Franklin HuangUniversity of California, San FranciscoMeningioma, Prostate, and Breast
Dawn Quelle; James Howe and Yusuf MendaUniversity of IowaNeuroendocrine Tumors
*Arul Chinnaiyan and Ganesh PalapattuUniversity of Michigan, Ann ArborProstate
Richard Gorlick and Phillip FutrealUniversity of Texas MD Anderson Cancer CenterSarcoma

*Grant Renewal    


Goals of the SPORE Program

  • Translating novel scientific discoveries from the laboratory and/or population studies to the clinic for testing in humans with cancer or at risk for cancer
  • Determining the biological basis for clinical observations
  • Using specimens from clinical studies to determine correlations between biomarkers and outcomes in patients
  • Promoting collaborations between SPOREs, Cancer Centers, other NCI/NIH funded mechanisms and programs, and outside organizations
  • Promoting pilot projects and career enhancement of researchers new to translational research
  • Supporting research in high incidence and rare cancers
  • Encouraging communication with advocates and advocate organizations to obtain advice from the patient perspective

Contact TRP staff for more information on the SPORE program.
 

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