Major Initiatives

 

The DCTD Programs and Initiatives Book (2018-2019) provides a comprehensive review of recent research findings across the division.

• Centralized Coordination and Standardization of Electronic Health Record (EHR) Pilot
• NCI Virtual Clinical Trials Office (VCTO) Pilot Program
• NCI-supported Precision Medicine Oncology Research Activities
• DCTD-supported Research Networks
  Extramural research networks that seek to advance precision medicine in oncology and cancer research in specific areas
• Developmental Therapeutics Clinic (DTC)
  Develops new treatments for patients with advanced cancer through innovative early-phase clinical trials.
• NCI Experimental Therapeutics (NExT) Program
  Advances clinical practice and brings improved therapies to patients with cancer by supporting the most promising new drug discovery and development projects.
• NCI Formulary
  Provides main-member ETCTN or NCTN investigators with rapid access to agents for on-site, investigator-held-IND clinical or preclinical research.
• NCI Patient-Derived Models Repository (PDMR)
  Provides early-passage, molecularly characterized, and clinically annotated patient-derived xenograft models to the scientific community.
• NCTN/NCORP Data Archive
  Provides access to a centralized repository of patient-level data from Phase 3 clinical trials.
• NCI Clinical Trials Stewardship Initiative
  Information on NCI's efforts to advance the public health impact of cancer trials through the implementation of key NIH policies affecting the conduct and management of NCI-funded clinical trials.

Cancer Diagnosis Program

• Precision Medicine Trials
• Molecular Characterization (MoCha) Lab
• Exceptional Responders
• CIMAC-CIDC
• Strategic Partnering to Evaluate Cancer Signatures (SPECS)
• TAILORx

Cancer Imaging Program

• The Quantitative Imaging Network
  Promotes research, development, and clinical validation of quantitative imaging tools and methods for the measurement or prediction of tumor response to therapies in clinical trials.
• The Cancer Imaging Archive (TCIA)
  Provides, de-identifies, and hosts a large archive of medical images of cancer that are accessible for public download.
• The Cancer Genome Atlas (TCGA) Imaging Genomics
  Provides image data collections that are matched to the genomically analyzed tissue cases in The Cancer Genome Atlas.

Cancer Therapy Evaluation Program

• An Overview of NCI’s National Clinical Trials Network
• NCI-sponsored Trials in Precision Medicine
• Intellectual Property Rights
• Experimental Therapeutics Clinical Trials Network (ETCTN)
• Pediatric Early Phase Clinical Trials Network (PEP-CTN)

Developmental Therapeutics Program

• NCI ALMANAC
• Repositories of Tumors and Tumor Cell Lines, Patient-Derived Models, Chemical Agents, Natural Products, and Biologicals
• Stepping Stones Initiative

Radiation Research Program

• Cancer Disparities Research Partnership Program
• Medical Countermeasures against Radiological and Nuclear Threats Program
• Radiation Bioterrorism Research and Training