Irina A. Lubensky, M.D.

Dr. Lubensky and her PIRB staff are responsible for management of multiple NCI multi-institutional cooperative agreement grants for biospecimen banking resources to support cancer research including Cooperative Human Tissue Network (CHTN), NCI Clinical Trials Network Biospecimen Banks (NCTN Banks), Early Experimental Trials Biospecimen Bank (EET Bank) as well as the NCI Specimen Resource Locator.

Dr. Lubensky joined the Cancer Diagnosis Program at DCTD/NCI in 2006 as a Chief of the Pathology Investigations and Resources Branch. After receiving her M.D. degree from Temple University School of Medicine, she completed her Pathology Residency, Surgical Pathology Fellowship and Post-doctoral Fellowship at the Hospital of the University of Pennsylvania in Philadelphia PA. She is certified by the American Board of Pathology.

Prior to joining CDP/DCTD, she served as a staff Surgical Pathologist and Chief of the Hereditary Cancer Syndrome Unit at NIH’s Laboratory of Pathology, intramural NCI, and as a translational researcher/staff scientist at the Surgical Neurology Branch, NINDS, NIH. For 14 years, Dr. Lubensky conducted molecular genetics and molecular pathology research on endocrine, gastrointestinal, kidney and brain tumors, and studied the pathogenesis of the hereditary tumor syndromes such as Multiple Endocrine Neoplasia, type1 (MEN1), von Hippel-Lindau syndrome (VHL), Zollinger-Ellison syndrome (ZES) and papillary renal cell carcinoma.

Selected Publications

• Chandrasekharappa SC, Guru SC, Manickam P, et al. Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science. 1997;276(5311):404-407.
• Zhuang Z, Ezzat SZ, Vortmeyer AO, et al. Mutations of the MEN1 tumor suppressor gene in pituitary tumors. Cancer Res. 1997;57(24):5446-5451.
• Lubensky IA, Schmidt L, Zhuang Z, et al. Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype. Am J Pathol. 1999;155(2):517-526. 
• Lubensky IA, Pack S, Ault D, et al. Multiple neuroendocrine tumors of the pancreas in von Hippel-Lindau disease patients: histopathological and molecular genetic analysis. Am J Pathol. 1998;153(1):223-231.
• Lubensky IA, Vortmeyer AO, Kim S, et al. Identification of tumor precursor cells in the brains of primates with radiation-induced de novo glioblastoma multiforme. Cell Cycle. 2006;5(4):452-456. doi:10.4161/cc.5.4.2482

Additional Links to Scientific Publications

• Google Scholar

Education

• M.D., Temple University School of Medicine, Philadelphia, PA
• B.A., Biology, University of Pennsylvania, Philadelphia, PA
• Resident, Anatomic/Clinical Pathology, and Fellow, Surgical Pathology, Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA
• Postdoctoral Fellow, Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Cancer Center, Philadelphia, PA