Aniruddha Ganguly, Ph.D.

Dr. Aniruddha Ganguly has responsibilities for providing guidance to the planning, development, implementation, and evaluation of assigned biomedical research programs including, molecular diagnostic technologies, extracellular RNA/exosome/extracellular vesicles in cancer diagnosis, brain tumor research and clinical trials, evaluation of Biomarker, Imaging and Quality of Life Studies Funding Program and core correlative science studies. He organizes and hosts Cancer Diagnosis Program Science Sessions. He has developed Program Project (P01) Development Guidance to support P01 investigators, particularly new investigators in their pre-application development stage. 

Before joining the NCI in 2011 as a Program Director, he served as an Assistant Professor at Harvard Medical School/Harvard University for many years directing and conducting cancer biology research, and teaching MD/DMD students. During that time, he discovered a new protein-protein interaction between CEA and a 115 kDa monocyte/macrophage protein that has implications in colon tumorigenesis. He supervised a CLIA certified Laboratory of the department of Pathology at Massachusetts General Hospital. His research was funded by NIH R01, Corporate and Foundation grants. He was scientific advisor of biotechnology companies.

He has expertise in mechanisms of tumor development and metastasis, tumor microenvironment, tumor cell-macrophage interactions, biospecimen processing and banking, cancer biomarkers, clinical assay development, molecular analysis technologies and informatics technology for cancer research, and cancer health disparities research. 

He received many awards including, Bharat Gaurav (Pride of India) (2010) from India, excellence in teaching awards (2007 & 2011) from Harvard Medical School, Partners in Excellence Award from Mass General Hospital/Partners HealthCare (2009), NCI Director’s Awards of Merit (2014 & 2015), and NIH Director’s Award (2024).

Selected Publications

• Gangopadhyay (Ganguly) A and Chatterjee S. A cell-cycle-phase-specific mutant of amoeba. J Cell Sci. 1984; 68:95-111. DOI: 10.1242/jcs.68.1.95
• Gangopadhyay (Ganguly) A, Bhattacharya M, Chatterjee SK, Barlow JJ and Tsukada Y. Immunoperoxidase localization of a high molecular weight mucin recognized by monoclonal antibody 1D3. Cancer Res. 1985; 45:1744-1752.
• Gangopadhyay (Ganguly) A, Bajenova O, Kelly TM and Thomas P. Carcinoembryonic antigen induces cytokine expression in Kupffer cells: Implications for hepatic metastasis from colorectal cancer. Cancer Res. 1996; 56:4805-4810.
• Ganguly A, Yeltsin E, Robbins J. Identification of a carcinoembryonic antigen binding protein on monocytes. Biochem. Biophys. Res. Commun., 2003; 311 (2): 319-323. DOI: 10.1016/j.bbrc.2003.09.213
• Amolegbe S, Johnston N, Ambrosi A, Ganguly A, Howcroft TK, Kuo LS, Labosky P, Rudnicki DD, Satterlee JS, Tagle DA, Happel C. Extracellular RNA Communication: A Decade of NIH Common Fund Support Illuminates exRNA Biology, J Extracellular Vesicles, 2025;14:e70016; DOI:10.1002/jev2.70016