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Last Updated: 04/07/2022

2022 American Association for Cancer Research Annual Meeting

Schedule of DCTD Presentations

DCTD-supported research will be presented at the AACR Annual Meeting External Link   from April 8-13, 2022.

The following tables include presentations containing DCTD staff speakers and co-authors.

Oral Presentations

Date/Time Title/DCTD Speaker ID
April 9
9:00 AM – 9:20 AM
Translation of omics predictors to clinically useful tests: Avoiding the pitfalls and paving the way to success External Link

Lisa M. McShane, PhD
ED022
April 10
1:00 – 2:00 PM
NCI Consortia Initiative: Response to Cancer Moonshot Recommendation to Establish a Network on Direct Patient Engagement - The Moonshot Biobank External Link

Helen Moore, PhD
NIH05
April 11
1:30 PM – 3:00 PM
Trust in Science External Link

Tracy Lively, PhD
FO06
April 12
9:30 AM – 10:30 AM
Meet the Editor-in-Chief, Molecular Cancer Therapeutics External Link

Beverly Teicher, PhD
Booth 2101
April 12
12:30 PM – 1:30 PM
NCI-Cancer Diagnosis Program Initiatives, Funding Opportunities and Resources for Investigators External Link

Aniruddha Ganguly, PhD, Lyndsay Harris, MD, Mickey Williams, PhD, Chris Karlovich, PhD
NIH09
April 12
2:30 PM – 3:30 PM
NCI Resource: The Frederick National Laboratory for Cancer Research and the NCI Program for Natural Product Discovery External Link

Barry O'Keefe, PhD
NIH10
April 12
5:00 PM – 6:30 PM
Breaking Down Silos; If we did it during the COVID pandemic, why not for cancer? External Link

James Doroshow, MD
FO04

Poster Presentations

Date/Time Title/DCTD Presenter (If Applicable) ID
April 8
12:00 PM – 1:00 PM
Inhibition of de novo and salvage pathways for dNTP synthesis enhances sensitivity to ionizing radiation in pancreatic neuroendocrine tumor cells External Link 5430
April 8
12:00 PM – 1:00 PM
NCI’s Clinical Proteomic Tumor Analysis Consortium: A proteogenomic cancer analysis program External Link

Mehdi Mesri, PhD
6331
April 10
1:30 PM – 5:00 PM
Genomic characterization of PDX models from rare cancer patients in the NCI Patient-Derived Models Repository External Link 80
April 11
9:00 AM – 12:30 PM
Comparative single cell transcriptome profiling of primary tumors, CTCs and metastatic sites from a bladder cancer PDX model External Link 973
April 11
9:00 AM – 12:30 AM
LIG1 deletion predicts chemotherapy resistance, chromosomal instability, and poor prognosis in triple negative breast cancer External Link 1010
April 11
9:00 AM – 12:30 PM
RAS-pathway inhibitors (Sotorasib, MRTX-1257, TNO-155, BI-3406) in a Complex Spheroid Combination Screen with PDMR Cell External Link

Naoko Takebe, MD, PhD
1054
April 11
9:00 AM – 12:30 PM
Screens of targeted agents combined with the ubiquitin activating enzyme inhibitor TAK-243 or the pan-Akt inhibitor ipatasertib identified combinations that are effective in patient-derived complex spheroids External Link 1055
April 11
9:00 AM – 12:30 PM
The Clinical Genome Resource (ClinGen) somatic cancer clinical domain working group External Link 1192
April 11
9:00 AM – 12:30 PM
A repository of PDX histology images for exploring spatial heterogeneity and cancer dynamics External Link External Link ; 1202
April 11
9:00 AM – 12:30 PM
Safety and efficacy of Anti-PD-L1 antibody MEDI4736 (durvalumab) in combination with capecitabine in patients with advanced solid tumors (DURVA+) External Link

Mohamad Adham Salkeni, MD
CT115
April 11
9:00 AM – 12:30 PM
Evaluation of the in vivo efficacy of the B7-H3 targeting antibody-drug conjugate (ADC) DS7300a: A report from the Pediatric Preclinical In Vivo Resting (PIVOT) program External Link LB061
April 11
9:00 AM – 12:30 PM
CT170 - A phase 1 / 2 study of olaparib in combination with ramucirumab in metastatic gastric and gastroesophageal junction adenocarcinoma (GEJ) External Link CT170
April 11
1:30 PM – 5:00 PM
Drug combination screening of Ipatasertib and Abemaciclib with other targeted agents in complex multicellular tumor spheroids from the NCI-60 and the National Cancer Institute’s Patient-Derived Models Repository External Link 1881
April 11
1:30 PM – 5:00 PM
Quality control workflows developed for the NCI Patient-Derived Models Repository using lowpass whole genome sequencing and whole exome sequencing External Link 1913
April 11
1:30 PM – 5:00 PM
Phase 1 study of recombinant interleukin 15 (rhIL-15) in combination with checkpoint inhibitors nivolumab and ipilimumab in subjects with refractory cancers External Link

Sarah J. Shin, MD
CT147
April 11
1:30 PM – 5:00 PM
BVD-523FB (Ulixertinib) in Patients with Tumors with BRAF Fusions, or with Non-V600E, Non-V600K BRAF Mutations: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Sub-protocol EAY131-Z1L External Link CT160
April 11
1:30 PM – 5:00 PM
Randomized phase 2 trial of sunitinib or cediranib in alveolar soft part sarcoma External Link CT168
April 12
9:00 AM – 12:30 PM
Integrating biospecimen science approaches in clinical assay development-PAR 22-049 External Link

Lokesh Agrawal, PhD
2791
April 12
1:30 PM – 5:00 PM
Development of an automated platform for screening patient-derived organoid models External Link 3079
April 12
1:30 PM – 5:00 PM
Patient-derived organoid drug responses corroborate known target-drug interactions for selected anticancer agents External Link 3091
April 12
1:30 PM – 5:00 PM
Method development for generation of PDX models from rapid autopsy samples for the NCI Patient-Derived Models Repository External Link 3120
April 13
9:00 AM – 12:30 PM
Demethylation, DNA damage and antitumor activity of DNA methyltransferase inhibitors in models with intact and disrupted DNMT1 gene External Link

Sherry X. Yang, PhD
LB192

Meet-the-Expert Presentations – Booth 1224

Date/Time Topic Presenter
April 11
12:00 PM
Cooperative Human Tissue Network (CHTN) & NCI National Clinical Trials Network (NCTN) Biospecimens Available for the Cancer Research Community Irina Lubensky, MD, CDP (presented by Aniruddha Ganguly, CDP)
April 11
2:30 PM
Opportunities for Cancer Research Support from Multiple NIH Institutes and Centers Morgan O’Hayre, PhD, DTP
April 12
2:30 PM
High Throughput Screening with Tumor Complex Spheroids and Organoids from the NCI PDMR Beverly Teicher, DTP
April 12
3:30 PM
NCI DCTD-Cancer Diagnosis Programs & Funding Opportunities Aniruddha Ganguly, CDP

Staff Kiosk Schedule – Booth 1224

Date Time Presenter
April 10 1:00 PM – 3:00 PM Aniruddha Ganguly, PhD
Cancer Diagnosis Program
  3:00 PM – 5:00 PM Lokesh Agrawal, PhD
Cancer Diagnosis Program
April 11 9:00 AM – 11:00 AM Morgan O’Hayre, PhD
Developmental Therapeutics Program
  11:00 AM – 1:00 PM Yali Fu, PhD
Developmental Therapeutics Program
  1:00 PM – 3:00 PM Sharad Verma, PhD
Developmental Therapeutics Program
  3:00 PM – 5:00 PM Aniruddha Ganguly, PhD
Cancer Diagnosis Program

Ana I. Robles, PhD
Office of Cancer Clinical Proteomics Research
April 12 9:00 AM – 11:00 AM Weiwei Chen, PhD
Developmental Therapeutics Program
  11:00 AM – 1:00 PM Connie Sommers, PhD
Developmental Therapeutics Program
  1:00 PM – 3:00 PM Sundar Venkatachalam, PhD
Developmental Therapeutics Program
  3:00 PM – 5:00 PM Marc S. Ernstoff, MD
April 13 9:00 AM – 12:00 PM Aniruddha Ganguly, PhD