The Cancer Imaging Program Convenes the Co-Clinical Imaging Research Program (CIRP) Annual Virtual Meeting 2022

The CIRP Network is a trans-NCI initiative designed to:

• Provide the broader cancer community with web-accessible research resources for quantitative imaging of co-clinical trials, which are investigations in patients and in parallel (or sequentially) in mouse or human-in-mouse models (e.g., genetically engineered mouse models or patient derived xenografts).
• Encourage consensus on how quantitative imaging methods are optimized to improve the quality of imaging results for co-clinical therapeutic or prevention trials of adult and pediatric cancer
• Leverage existing NCI resources and programs to ensure best practices, effective outreach, and rapid dissemination

The CIRP Annual Virtual Meeting 2022 convened on June 22-23 and brought together stakeholders from academia, industry, scientific communities, and federal agencies, plus the following nine CIRP U24 teams and one Informatics Technology for Cancer Research (ITCR) U24 team:

• Washington University at St. Louis
• Duke University
• MD Anderson Cancer Center
• University of Pennsylvania
• University of Michigan
• Baylor College of Medicine joined by University of Texas at Austin and Stanford University
• University of California at San Francisco
• Stanford University
• University Washington/Fred Hutchinson Cancer Research Center/Brigham and Women's Hospital,
• ITCR team from Washington University at St. Louis

Meeting Mission

Review the progress of the CIRP program, demonstrate CIRP web resources, identify challenges in the four essential areas of the CIRP (animal models, co-clinical trials, quantitative imaging, and informatics), and seek solutions to integrate data, harmonize protocols, and/or standardize methodology

Meeting Topics

• CIRP program updates
  • Progress reports and 21 poster briefings from the nine CIRP teams, one associate member supported by NCI ITCR program, and two associate members
  • Demonstrations of web-resource development from the seven CIRP teams
• CIRP Steering Committee and three working groups updates
  • Specific issues in animal models and co-clinical trials, emerging photon counting CT technology, Bigimage space, and NCI Imaging Data Commons
  • Special issues related to using animal models in co-clinical trials, preclinical imaging protocols, use of standardized phantoms in preclinical MRIs, information collected in web resources, small animal DICOM and metadata, and interoperability in preclinical imaging
• Closed business management session for the CIRP Steering Committee

For the complete meeting agenda and more information on CIRP, contact Huiming Zhang, PhD (zhanghui@mail.nih.gov ).