The top of the figure shows a diagram of North Carolina which displays shaded areas in yellow, green and purple. These colors represent different census tracts in regions of the Carolina Breast Cancer Study indicating levels of community advantage and disadvantage. The lower part of the figure represents an overview of the Joint model which integrates individual and contextual factors along with molecular traits for model building. This diagram includes a multicolored square at the top with the letter "Z" at its center. To the left of the square are two circles, each with arrows pointing towards the "Z". The top circle contains the symbol delta while the bottom circle contains the symbol sigma. Below these circles is a green vertical diamond labelled "Registration". From the top point of the diamond, 2 green lines extend. One points to the delta circle and the other points to the sigma circle. Beneath the square is a bidirectional arrow. Under the biodirectional arrow are three squares in a row. This arrow points to a square containing tiny multicolored human shaped icons and a "X" in the center. At the top left corner of the "X" box is a circle with an arrow pointing to it containing the letter "Beta". To the left of the "X" box is a blue box with a "W" in the center that includes images of a chemical structure, buildings and the outline of a human figure with an arrow pointing toward the "X" box. To the right of the "X" box is a white box with a "Y" in the center. This box features a line graph with red and blue lines descending toward the right. There is an arrow from the "X" box pointing to the "Y" box and is a circle with an arrow pointing toward it containing the letter upsilon.