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Last Updated: 11/10/2015

DCTD Researchers Presented Data at the International Conference on Molecular Targets & Cancer Therapeutics (Nov 5-9, 2015; Boston, MA)

Several DCTD researchers presented new data at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics External Link (November 5-9, 2015; Boston, MA).

James H. Doroshow, MD, NCI Deputy Director for Clinical and Translational Research and Director of the Division of Cancer Treatment and Diagnosis, co-chaired a plenary session entitled, "The In Vitro Patient" External Link . During this session, Dr. Doroshow presented information on NCI's patient-derived models repository External Link , which will be available for public use in 2016.

DCTD researchers also were involved in studies presented during the meeting's poster sessions:

Characterization and Enumeration of Multiple Circulating Tumor Cell Phenotypes Using Two Distinct Platforms Establishes Presence of Epithelial-Mesenchymal Transition CTCs in Patients External Link
Wang L, Owusa F, Khin S, Parchment R, Chen A, Kummar S, Doroshow JH, Kinders RJ

Epithelial to mesenchymal transition in human tumor biopsies: Quantitative, histopathological proof of the existence of EMT in vivo by immunofluorescence microscopy External Link
Navas T, Kinders RJ, Lawrence SM, Ferry-Galow K, Pfister TD, Srivastava AP, Alcoser SY, Hollingshead MG, Dutko LM, Gouker BA, Butcher DO, Makhlouf H, Chuaqui R, Bottaro DP, Kummar S, Chen A, Doroshow JH, Parchment RE

DNA methyltransferase 3A expression in cancer cells following treatment with DNMT inhibitors and in human solid tumors External Link
Yang SX, Nguyen D, Rubinstein L, Chen AP, Doroshow JH

Initial testing (Stage 1) of EPZ-6438 (tazemetostat), a novel EZH2 inhibitor, by the pediatric preclinical testing program (PPTP) External Link
Kurmasheva K, Cosmopoulos K, Sammons M, Favours E, Wu J, Houghton P, Smith M

Radiation-inducible molecular targets in a human prostate cancer mouse model External Link
Makinde AY, Eke I, Aryankalayil MJ, Ahmed M, Coleman CN

Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression External Link
Teicher BA, Polley E, Kunkel M, Evans D, Silvers T, Delosh R, Laudeman J, Ogle C, Reinhart R, Selby M2, Connelly J, Harris E, Monks A, Morris J