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U.S. National Institutes of Health
Cancer Diagnosis Program Cancer Imaging Program Cancer Therapy Evaluation Program Developmental Therapeutics Program Radiation Research Program Translational Research Program Biometric Research Branch Office of Cancer Complementary and Alternative Medicine
Last Updated: 04/25/2012


Synthetic Products Repository

Since this repository began about 50 years ago, more than 500,000 proprietary and nonproprietary compounds have been submitted to the program. In addition to being a repository for NCI screens, the repository distributes compounds for research purposes both as specific vialed compounds and in plated sets for high-throughput screening.

DTP’s plated sets have been instrumental in the discovery of compounds that enhance antilymphoma activity, nucleic acid antagonists with anti-HIV activity, and inhibitors of angiogenin—to name a few important advances.

The Synthetic Products Repository has recently developed a plated set to help evaluate drugs in combination. NCI’s Pediatric Preclinical Testing Program will be one of the first groups to use the new plated sets; the results of the studies will be posted on DTP’s open-use website at: