This repository, an NCI-sponsored facility, stores bulk cytokines, monoclonal antibodies, and cytokine standards under carefully controlled conditions. The repository provides a constant and uniform supply of high-quality reagents to nonprofit institutions and qualified commercial establishments at no charge. This facility obtains new materials by donation or at reduced cost by negotiating with companies and investors. To date, the Biological Resources Branch Preclinical Repository has distributed more than 40,000 samples, and the estimated value of materials shipped to investigators is about $100,000 per year.
For researchers who hold a valid radioactive materials license, there are roughly 90 radiolabeled drugs available from DTP’s Radiolabeled Materials Repository. Radiolabeled compounds are instrumental in noninvasive studies of biodistribution and in target pharmacokinetics of therapeutics.
DTP’s Pharmaceutical Resources Branch bears the responsibility of acquiring bulk materials for formulation and synthesis, formulating drugs and testing them, producing clinical dosage forms, and stability testing of clinical dosage forms. This branch provides clinical researchers, both academic and institutional, with top-quality drugs for clinical trials and formulates drug compounds that are under development by the DDG or the RAID program.