This link provides a detailed, yet simple guide entitled “How to Find a Cancer Treatment Trial,” which helps patients to:
This is the entry to the NCI’s database of cancer clinical trials. Protocol summaries are provided in lay language for patients and in a more detailed format for health professionals. A search form for the database is provided, and an advanced search feature is also available.
This link provides the means for monitoring progress in cancer care by providing summaries of recently released results from cancer clinical trials that may affect medical care. The summaries are listed in reverse chronological order. Navigation tools allow searching by keyword or type of cancer. The site also includes links to other patient information materials.
This website provides regularly updated information about federally and privately supported clinical research in human volunteers. It includes all diseases and gives information about a trial’s purpose, who may participate, locations, and phone numbers for more details.
This link provides the visitor with information on a new NCI initiative to collect all NCI funded clinical trial data into one central repository. The objective of the CTRP is to retain this information in one central database allowing NCI leadership to better manage its extensive portfolio of clinical trials it sponsors and to provide the information to allow for the development of high quality, high impact clinical trials.
From the early days of the NCI’s National Cancer Chemotherapy Service, which was the original name of the NCI’s clinical trials network, investigators from the United States and Canada have collaborated in the development and conduct of clinical trials. More recently, academic sites and Cooperative Groups elsewhere in the world have joined these efforts. Clearly, the participation of more sites and more investigators in clinical trials will permit faster accrual and thus faster answers to clinical questions. In addition, international participation will permit the NCI to leverage public investment in clinical trials infrastructure in many countries both for rare and common diseases. Challenges to greater international collaboration include regulatory and administrative barriers. CTEP staff are working closely with investigators and program staff in many other countries to determine how best to overcome these barriers.
The purpose of this effort is to identify and remove barriers to effectively working with international partners to develop cancer clinical trials. As adult enrolment in clinical trials is less than 5 percent and cancer climbs to the number one cause of death worldwide, the need to expand the recruitment of patients into clinical trials has become of paramount importance to investigators. Greater collaboration intends to accelerate the rate of new discoveries in the fight against cancer.
In 2011, NCI created the Center for Global Health (CGH) (http://www.cancer.gov/aboutnci/globalhealth) to support the Institute-wide goal of advancing global cancer research, building expertise, and leveraging resources across nations to address the challenges of cancer and reduce cancer deaths worldwide.
As lack of health insurance coverage is a barrier for patient participation in cancer treatment trials, this link provides information for to help understand coverage issues. Information includes:
The Centers for Medicare and Medicare Services (CMS) and NCI have been collaborating on a pilot program that ensures beneficiaries rapid access to promising new uses of technologies under controlled clinical trial conditions. CMS issued a National Coverage Determination (NCD) to cover the off-label use of certain anti-cancer drugs and nine specific CTEP-sponsored clinical trials of colorectal cancer and other cancer types were identified for Medicare to provide coverage. This pilot has been successful as approximately one third of the patients participating in these 9 NCI-CMS trials have been age 65 or older, a significantly larger proportion of older patients on trials than is typically seen. It has been challenging to recruit older individuals to clinical trials, despite the increasing incidence of cancer with age. The results from this pilot suggest that lack of insurance coverage is an important barrier.